Sustained-release preparations and medication errors

Current Advances in Sustained-release Injectable Preparations

In recent years, there has been a great deal of interests in developing sustained-release systems which can prolong the therapeutic effect, decrease adverse side effects, and reduce administration frequency. Nowadays, the oral sustained-release preparations account for a larger market share comparing to other sustained-release forms, mainly because of its noninvasive pain-free administration. H...

Narcotic antagonists: naltrexone pharmacochemistry and sustained-release preparations.

Introduction to medication errors and medication safety

A medication safety incident is defined by the National Patient Safety Agency (NPSA) as: ‘any unintended or unexpected incident which could have or did lead to harm for one or more patients’ (NPSA, 2007:9). These incidents can occur at each stage of the process involved in the delivery of medicines to patients, i.e. prescribing (including transcribing or physician ordering), dispensing, prepara...

Formulation and Evaluation of Sustained Release Matrix Tablets of Glipizide

      The purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. Two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose K 100 (HPMCK) and Eudragit L 100. The granules were prepared by wet granulation method and thereby formulated as F-1, F-2. F...

Medication Errors and its Contributing Factors among Midwives

Introduction: Medication errors are among the most serious health errors threatening patient safety in all countries, with major impacts on public health. Midwives as members of healthcare systems are prone to such errors. Therefore, in this study, we aimed to determine medication errors and the contributing factors among midwives working in maternity units of Mashhad University of Medical Scie...